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Sandra Cauwenberghs Selected Research

Neoplasms (Cancer)

12/2018Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy.
12/2017Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate.
2/2011Vessel abnormalization: another hallmark of cancer? Molecular mechanisms and therapeutic implications.

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Sandra Cauwenberghs Research Topics

Disease

4Thrombosis (Thrombus)
10/2007 - 02/2006
3Neoplasms (Cancer)
12/2018 - 02/2011
2Leukemia
01/2020 - 06/2011
1Pathologic Neovascularization
01/2014
1Necrosis
01/2013
1Hyperlipidemias (Hyperlipidemia)
05/2012
1Vascular Diseases (Vascular Disease)
05/2012
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2011
1Inflammation (Inflammations)
06/2008
1Thrombocytopenia (Thrombopenia)
02/2007

Drug/Important Bio-Agent (IBA)

2Imatinib Mesylate (Gleevec)FDA Link
01/2020 - 06/2011
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014 - 02/2011
1LigandsIBA
12/2018
1PF-06840003IBA
12/2018
1Blocking AntibodiesIBA
12/2018
1KynurenineIBA
12/2018
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
12/2017
1EnzymesIBA
12/2017
1Tryptophan (L-Tryptophan)FDA Link
12/2017
1Complement System Proteins (Complement)IBA
01/2013
1CX3C Chemokine Receptor 1IBA
05/2012
1Chemokine ReceptorsIBA
05/2012
1Oxygen (Dioxygen)IBA
02/2011
1SialyltransferasesIBA
06/2008
1Hemostatics (Antihemorrhagics)IBA
10/2007
1ThrombinFDA Link
02/2007
1Purinergic Receptors (Receptors, Purine)IBA
06/2006
1CollagenIBA
02/2006
1P-SelectinIBA
02/2006
1Adenosine Diphosphate (ADP)IBA
02/2006

Therapy/Procedure

3Therapeutics
12/2018 - 02/2007
2Drug Therapy (Chemotherapy)
02/2011 - 02/2007
1Immunotherapy
12/2018
1Platelet Transfusion (Blood Platelet Transfusions)
02/2007